Joseph Gordon-Levitt & Seth Rogen: '50/50' Trailer!

Joseph Gordon-Levitt gets his head shaved by Seth Rogen in the trailer for their upcoming movie 50/50, in theaters September 30.

50/50 is an original story about friendship, love, survival and finding humor in unlikely places. Joseph and Seth star as best friends whose lives are changed by a cancer diagnosis.

The film draws its emotional core from director Will Reiser‘s own battle with cancer.

“Ideally we wanted to make a film that would be as funny, sad, and hopefully as honest as the experience we went through. As soon as the script was completed, it quickly became a passion project for all of us. It helped us come to terms with Will‘s struggle as well as our own experiences,” Seth said.

50/50 also stars Anna Kendrick and Bryce Dallas Howard.