Reese Witherspoon Set to Star in 'Rule #1'

Reese Witherspoon arrives at LAX Airport with her two kids, Ava and Deacon, on Monday (November 14) in Los Angeles.

The 35-year-old actress has signed on to star in the comedy Rule #1, which will be directed by Oscar nominee Courtney Hunt.

PHOTOS: Check out the latest pics of Reese Witherspoon

The flick “tells the story of a 34-year-old woman trying to cope with OCD, who takes in a young woman with ADD and her newborn baby in an effort to face her anxieties and ultimately get her estranged husband back. The resulting effort takes the woman’s already chaotic world spinning into the next level,” according to THR.